The Vulthoo Gunship is a highly effective combatant against enemy ground units early on. Late-game almost any ground attack will include anti-air (Rock Head Tanks, Titans, Meteors, and Demolishers all gain anti-air upgrades, Cybran players will bring Adaptors, and Illuminate groups include Crahdows or even Airnomos), but early on few players will dedicate resources to traditionally weak mobile anti-air units. Keeping this in mind means that even a few gunships can easily and effectively level almost any early ground force, especially considering their high damage output.
The Vulthoo, like all gunships, flies low enough to attack from inside enemy shields. Use their high attack power directly on the shield generators to quickly shut down enemy defenses.
As a gunship, the Vulthoo has no ability to fire on most aircraft (though it can engage other gunships). Air to air weapons such as the Wasp Air Superiority Fighter will readily destroy Vulthoos, even in large numbers.
As gunships don't need to make sweeping passes to attack (unlike bombers) they make ideal units for attacking vulnerable parts of an enemy base with. Use their combination of power and precision to exploit minor weaknesses in an enemy base, particularly flanks and exposed mass extractors outside the range of emplaced anti-air.
Gunships pack a great deal of health and firepower for their cost, and can apply precision outside the scope of most other units. These traits make them incredibly effective against enemy ACUs when moving in groups. A medium-large number of gunships (typically fourteen or more) can usually destroy an enemy ACU even in the presence of anti-aircraft weapons.
Approximately eight or nine Vulthoos can destroy an equally upgraded anti-air turret without suffering more than one casualty, none if upgraded with shields. Use this metric to limit losses to your air groups.
Later on the Vulthoos gets a flare upgrade which will soak up damage, when used in great numbers included with flares they can take down any target which is not extreme turtled (20+ AA towers).
Even with Flares, the Vulthoo is very weak to Anti-Air fire. This is because, unlike a bomber which dodges, it more or less stays in place.
a teleport research upgrade is included in the infinite war battle pack one DLC for illuminate air units. use this as a suprise attack/retreat plan to make up for its lower speed compared to fighters/bombers.